Opening up new dimensions of Interaction

Intriguing research has been done to better understand our brain, and directly have it interface with computers. However, most students, researchers, developers or creative minds did not have access to the knowledge we have built up as humanity, because it has not been productised.

We have bundled out knowledge (gained in helping locked-in patients) in an open-source project: allowing anyone with basic development skills to build their own BCI-application, and do further research into its uses for our common future.   For ideas on what is possible with this technology check out our you-tube channel.


With our open-source code, you are able to make your own Brain Computer Interface (BCI) application that is reliable, fast and requires no training.


With our solution, one wears a headset that measures electrical brain activity. Through visually directing one’s attention at specifically designed stimulus, such as the special keyboard in the video-clip, the BCI matches the brain signals with the stimulus. This allows you to spell letter by letter with your brain. This method is fast, reliable and requires no training.


  • Fast: detection in ~2 second
  • Reliable: 95% accuracy
  • Easy: no training necessary
  • Robust: insensitive to movement artifacts
  • Flexible: can combine on-screen and physical objects


Our patented BCI technology is easy to integrate with other technologies making it suitable for a range of applications that may benefit both patients and caretakers, but can also entertain a broader public, with the amazing possibilities we are developing. Check out our Labs page to get an idea of the possibilities.

We had a successful KickStarter campaign, and have decided afterwards to publish our software under an open-source license, and write tutorials how to assemble the hardware and create applications. You can find it here and this blog post explains how to work with it.


Jason Farquhar

CTO, Head of Machine Learning

Jennifer Goodall


Khash Sharif

Embedded software engineer

Mark van Kesteren

Software engineer

Ivo de la Rive Box


Peter Desain


Bert-Arjan Millenaar

Founder & CEO NLC

Lars Olthoff

NLC, Venture Finance Specialist


We are hiring people who can come join us in our new offices in Ede!  Checkout our Careers page for more details.


About Us


We want to develop and apply Neuro-Technologies to solve the pressing problems of humanity with a focus on the health-care sector.  In particular, we develop technologies based on measuring and understanding neural signals, to help people better understand themselves, or enhance their interactions with the world.

What is MindAffect?

Our team works on the cutting-edge of artificial intelligence and neuroscience. We have developed a BCI and demonstrated that it allows locked-in patients to interact or communicate by controlling a computer with brain signals. MindAffect was spun-out of the Donders Institute as a start-up in September 2017.

Where is it going?

We are working on applications of neuro-tech in diverse markets such as; 

  • Neural based sensory testing, in vision, hearing and touch
  • Brain Computer Interfaces for patient communication and control
  • Neural response testing for Brain Health Monitoring

For more information on our current application areas see

Scientific Advisory Board

University of Vienna

Research Group Neuroinformatics / Faculty of Computer Science

Prof. Moritz Grosse-Wentrup

Inria Bordeaux Sud-Ouest

BCI Research Scientist

Fabien Lotte, Ph.D.

Tokyo University of Agriculture and Technology

Institute of Global Innovation Research

Toshihisa Tanaka, Ph.D.

National Center for Adaptive Neurotechnologies

Research Scientist

Theresa Vaughan, B.A.


Donders Institute

The Donders Institute is part of the Radboud University Nijmegen in The Netherlands. It has undertaken the research in the areas of neuroscience and artificial intelligence that has formed the basis of MindAffect.


NLC is a healthtech venture builder based in Amsterdam, The Netherlands. It has validated the market for MindAffect.

ALS Associations

This website and our efforts have been made possible by the generous support of the ALS associations of 🇺🇸, 🇧🇪 and 🇳🇱, ao under Grants ATC20610 and 18-SCH-391

EIT Health

EIT Health Accelerator is a business creation programme, set up to support the best and brightest health industry entrepreneurs. EIT Health is supported by EIT, a body of the European Union.

Province of Gelderland

We thank the Province of Gelderland for its generous support of our venture